食品伙伴網(wǎng)訊 據(jù)歐盟食品安全局(EFSA)消息,7月15日歐盟食品安全局發(fā)布了日落黃(E 110)臨時 ADI值的重新審查結果以及精確暴露評估。
歐盟專家組在對28天試驗以及毒理學評估進行研究的基礎上認為,將日落黃的臨時每日允許攝入量量(ADI)由 1 mg/kg bw /day 修改為 4 mg/kg bw /day,與食品添加劑專家委員會的意見一致,不會造成安全問題。在現(xiàn)有MPLs與使用水平之下,人群的暴露量低于 4 mg/kg bw /day。
部分原文報道如下:
The ANS Panel has considered that the newly submitted data from the 28-day study and the overall available toxicological database on Sunset Yellow FCF provides a basis to revise the established temporary ADI and concluded that, based on the NOAEL of 375 mg/kg bw/day from the long-term feeding study in rats and an uncertainty factor of 100, a new ADI for Sunset Yellow FCF of 4 mg/kg bw/day can be established, in agreement with the latest evaluation by JECFA.
Exposure estimates for Sunset Yellow FCF based both on the currently authorised MPLs and reported use levels provided are well below the new ADI of 4 mg/kg bw/day for all population groups. Overall, the Panel concluded that, using data provided by the food industry and Member States, the reported uses and use levels of Sunset Yellow FCF (E 110) would not be of safety concern.
Overall, the Panel concluded that using data provided by the food industry and Member states, the reported uses and use levels of Sunset Yellow FCF (E 110) would not be of safety concern.
原文鏈接:<http://www.efsa.europa.eu/en/efsajournal/pub/3765.htm>