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歐盟評估轉(zhuǎn)基因釀酒酵母菌株LALL-MA+生產(chǎn)的葡聚糖1,4-α-麥芽水解酶的安全性
日期:2024-08-08  來源:食品伙伴網(wǎng)
   食品伙伴網(wǎng)訊  2024年8月5日,歐盟食品安全局就一種葡聚糖1,4-α-麥芽水解酶(glucan 1,4-α-maltohydrolas)的安全性評價(jià)發(fā)布意見。
 
  據(jù)了解,這種食品酶是由轉(zhuǎn)基因釀酒酵母菌株LALL-MA+生產(chǎn)的,旨在用于谷物和其他谷物的加工,以生產(chǎn)焙烤產(chǎn)品。
 
  經(jīng)過評估,專家小組認(rèn)為,在預(yù)期的使用條件下,不能排除飲食暴露引起過敏和誘發(fā)反應(yīng)的風(fēng)險(xiǎn),但這種情況發(fā)生的可能性很低。根據(jù)所提供的數(shù)據(jù),評估小組得出結(jié)論,這種食品酶在預(yù)期使用條件下不會引起安全問題。部分原文報(bào)道如下:
 
  The food enzyme glucan 1,4-α-maltohydrolase (4-α-d-glucan α-maltohydrolase; EC 3.2.1.133) is produced with the genetically modified Saccharomyces cerevisiae strain LALL-MA+ by Danstar Ferment AG. The genetic modifications do not give rise to safety concerns. The food enzyme is free from viable cells of the production organism and its DNA. It is intended to be used in the processing of cereals and other grains for production of baked products. Dietary exposure was estimated to be up to 0.014 mg TOS/kg body weight per day in European populations. Given the QPS status of the production strain and the absence of concerns resulting from the food enzyme manufacturing process, toxicity tests were considered unnecessary by the Panel. A search for the identity of the amino acid sequence of the food enzyme to known allergens was made and four matches were found, three with respiratory allergens and one with an allergen from mosquito (injected). The Panel considered that the risk of allergic reactions upon dietary exposure cannot be excluded, but the likelihood is low. based on the data provided, the Panel concluded that this food enzyme does not give rise to safety concerns, under the intended conditions of use.
 
  本文由食品伙伴網(wǎng)食品資訊中心編輯,有任何疑問,請聯(lián)系news@foodmate.net。
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