食品伙伴網(wǎng)訊 2023年8月2日,據(jù)歐盟食品安全局(EFSA)消息,應歐盟委員會要求,歐盟動物飼料添加劑和產(chǎn)品(FEEDAP)研究小組就一種內切-1,4-β-木聚糖酶(endo-β-1,4-xylanase)作為所有禽類、仔豬和小型生長豬種飼料添加劑的安全性和有效性。
據(jù)了解,該添加劑是由Komagataella phaffii CGMCC 7.371 生產(chǎn)的。經(jīng)過評估,專家小組認為在建議的使用條件下該添加劑對目標物種、消費者和環(huán)境是安全的。該小組認為,在2000 U/kg全價飼料的劑量下,該添加劑對產(chǎn)蛋鳥類和仔豬(哺乳和斷奶)是有效的,在1000 U/kg全價飼料的劑量下,對所有其他鳥類是有效的。部分原文報道如下:
Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of endo-β-1,4-xylanase (VTR-xylanase) as a zootechnical feed additive for all avian species, piglets (suckling and weaned) and minor growing porcine species. VTR-xylanase is available in a powder and a liquid form and is produced by a genetically modified strain of Komagataella phaffii (CGMCC 7.371). The genetic modification of the production strain does not give rise to safety concerns. Viable cells of the production strain and its DNA were not detected in the final products. The additive does not pose any safety concern regarding the production strain. VTR xylanase (powder/liquid) produced by Komagataella phaffii CGMCC 7.371 is safe for all avian species, piglets and minor growing porcine species at the proposed conditions of use. The use of both forms of the additive under assessment in animal nutrition under the proposed conditions of use raises no safety concerns for consumers or for the environment. The liquid and powder formulations of VTR-xylanase are non-irritant to eyes but should be considered skin sensitisers. No conclusions can be drawn on the potential of the final formulations of the additive to be irritant to skin. Due to the proteinaceous nature of the active substance, the additive is a respiratory sensitiser. The additive has the potential to be efficacious in all laying birds and piglets (suckling and weaned) from all Suidae at 2,000 U/kg and in all other avian species/categories at 1,000 U/kg feed.
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